Saturday, November 9, 2019
POS
Disease concept note: polycystic ovary syndrome A lot of females worldwide tend to naturally shy off the topic of their genital health. They only come out of this devastating cocoon when the situation is far out of hand and beyond control, deeper analysis into this matter will add water to the myth that mortality rates in females are higher become they are ignorant of the most basic diseases. In matters pertaining reproductive health; the general public usually has very small information of the diseases that affect them (dunaif-1997). The general public is usually satisfied with knowledge of the most common sexually transmitted diseases; gonorrhea, syphilis, genital herpes and chancroid. This information is so trivial in such a vital topic. Apart from the general genitalia disease symptoms, females should be more cautious about their general health as their bodies are prone to bacteria and viruses compared to men.In this concept note I will be dissecting a not so common disease with very common symptoms that females ignore and only speak out when the symptom worsens. This note is meant to help doctors and nurses remedy the situation. To give it an authentic touch I did a web search from reputable institutions and contrasted the findings with one medical analysis I did on a patient. Signs and SymptomsIrregular menstrual cycleIrregular cycle means there is a delay in the monthly periods or having more than one menstrual cycle in a month. A female's regular cycle is usually 28 days. This statistic may differ a little bit in women as their bodies function differently despite having the same genetic traits and metabolic systems. When a patient highlights missing periods after her pregnancy test was negative most doctors are left with a wide range of diseases to ponder on. Among the common diseases that can cause delay of the menses are urine fibroids, pelvic inflammatory disease and thyroid cancer. Polycystic ovary syndrome is always denoted by delayed menstrual cycles.Acne breakoutThis is one of the most outstanding symptoms as it is accompanied by an increase in body temperature. The acne appears and disappears sporadically on the body. If a woman above 40 years complains of severe acne breakout then polycystic ovary syndrome should be tested first.Excess hair growth on the faceWomen faces are normally less hairy than men's' faces so a woman should be really alarmed when she notices rapid hair growth on her ears, nose and most of the time chin. This mostly affects women that have just hit 30 years and have contracted the disease.Restlessness and Sleepless nightsThis usually happens as patients having this disease exhibit high stress levels and cannot willingly focus on sleep or concentrate clearly. A slight interruption when the patient is sleeping makes her lose sleep completely. Rapid weight gain or weight lossDue to irregular hormone supply and imbalance, the metabolism in women will tend to change. The change will vary among the lot as they have different metabolic systems. No matter the case, drastic change in weight always mirrors unseen effects of a disease. Causes Withdrawal effects of family planning methods affect women hormonal systems and this in turn distorts the regular ovulation breakdown cycle. The effects if not medicated can be severe to the point of making the woman in question barren.MedicationFemale Patients under intense medication for long term diseases like cancer, diabetes and tuberculosis often experience delayed menses as their systems have to counter the effects of their prescribed dosages. Stress This is among the most ignored cause of polycystic ovary syndrome yet it holds bearing to a major symptom; restlessness and lack of sleep. A female's frequent exposure to stress prone environments alters the functionality of her limbic system and further her stress then menstrual pattern. Remedies There are natural and medical remedies to this disease.The natural remedies should be tested first then medical to follow later if the later has not helped relieve the symptoms. A keen analysis should be done on the patient to ascertain which Medicine prescription is suitable for her. This will prevent further severity of the underlying symptoms. Natural remedies Eating a balanced diet will help stabilize the metabolic system hence restore the females menses cycle. Pineapple and papaya fruits are a recommendation as they have bromeliad that breaks down uterus walls and flashes out any blockages along the way. A patient should also consider eating small quantities of food regulaly.Regular exercises like yoga and crossfit are good for kick starting the brain. Any workout is good as long as it is regular and comfortable.Distress and self-care will help activate the brain cells. One should at least take time and break from her regular routine. Even a 30 minute break can be very relieving. Reduce salt and caffeine consumption. These two food stuffs inhibit the production of hormones and if not moderated they tend to alter the female reproductive system Medicine recommended are tranexamic acid systematic popularly known as Lysteda. It is a miscellaneous coagulant modifier that helps in restoring back damaged cells in the body. Ethynyl estradiol commonly known as Drospirenone is a drug meant to reverse the withdrawal effects of contraceptives in women.Mineral and vitamin supplements can also be prescribed as their role is to stabilize the production of hormones in the body. References Source of remedies for polcystic ovary syndromehttps://www.drugs.com/condition/menstrual-disorderSource of detailed symptoms to the diseasehttps://rubycup.com/all-about-your-periods/irregular-periodsSource of other genital diseaseshttps://www.healthcommunities.com/menstruationInsulin resistance and the polycystic ovary syndromeEndocrine review by A Dunaif
Thursday, November 7, 2019
buy custom Protecting our Streets essay
buy custom Protecting our Streets essay First, we have to understand what anyone would mean by the term invasion of privacy.This term can mean the violation of ones right or the intrusion into a persons private life without their consent. This can be through physical intrusion or through surveillance using cameras (Elvik Hoye, 2009). The surveillance cameras could be hidden or made public in that the person becomes aware of the absence of privacy in advance or the person is not aware of the absence of privacy, but learns about it later. This brings in the case of usage of traffic lights and cameras on the roads. There are different views on this, since some people conceive the cameras as an invasion to their privacy, while others view them as purely for security on the streets and roads (Mathieu, 2008).This essay tries to argue out whether the traffic lights and cameras are really a privacy concern or a road safety and security measure in towns and cities. Traffic Lights and Cameras Looking at the question with an open mind, one perceives both arguments as rational. First, the idea of being watched every time by a systematized and centralized people with power and a large degree of control over your life sends chills over ones body and sounds more scary than being watched by disorganized people on the street. This means that no one can ever be comfortable with the cameras everywhere on the streets. Disturbing news as they may sound, the public street lights may have the ability to record conversations followed by the ability to broadcast government warnings and put across advertisements about all security issues (Mathieu, 2008). On the other hand, the cameras can undertake x-rays in search for concealed weapons. Privacy infringement is obvious with the cameras ability to record, monitor and display almost everything. On the other hand, the increase of guard rails and road signs cluttering the streets have different aims and have no intention of invading privacy at all. In short, the traffic lights are not about privacy since no individual with a legal and valid license will be expecting privacy on a public street. Some of the intentions of the street lights are to segregate the pedestrians from the vehicles, thus, it provides a degree of safety to the pedestrians (Mohan, Tiwari, Khayesi, 2006). The traffic lights and cameras serve as monitors against those drivers who mind the presence of others on the streets and, therefore, ensure a level of safety on the streets (Elvik Hoye, 2009). However, the necessity of this comes at an expense; the loss of privacy on the streets for those individuals who would prefer it. Although it is important to monitor traffic through the traffic cameras and lights, the concern erupts when the use is extended to streets in residential areas. It is logical to underst and that the residential streets tend to have a higher level of crime than other areas in towns and cities. The attempt to reduce the crime levels in these areas brings about the privacy intrusion concerns. The reason for this is that the security departments try to install security cameras and lights on the streets, but end up violating the fundamental right and need of being left alone. The cameras penetrate to residential areas and homes to the concern of many as they feel watched in all aspects. According to Smith Pack (2002), most of the cameras are installed in high crime areas. The American Civil Liberties Union (ACLU) confirms that some of them are powerful to the extent of being zoomed to reading a book and have the ability of tracking and locating people and vehicles as well as searching particular images from a distance. Basically, this is advanced levels of security enhancement but at the same time the feeling of privacy is definitely eluded. If a security camera can be zoomed to reading a page in a text book in a residential area, then one will be aware of the fact that there is nothing like privacy in that area as the camera can observe everything that one does. All conversations in residential areas and streets with the cameras are viewed, analyzed and recorded for security scrutiny (Mathieu, 2008). This is a total infringement of personal privacy, but absolutely necessary for security purposes. Considering other options through which the police can administer security on the streets except street lights and high resolution surveillance cameras, it wasdiscovered that they are very cost effective and they have no intention of privacy intrusion. Today, most streets are under observation unlike it was in the past. This is a prudent step to ensuring our public security by applying the appropriate measures to guarantee conformity to road traffic safety and protection regulations. The presence of the street lights and cameras enhances a degree of freedom and security to individuals and pedestrians who feel they now have freedom of movement. This freedom of movement motivates every individual to fit in place with each other so as to avoid one user group having an automatic priority or advantage over the other (Mohan, Tiwari Khayesi, 2006). Consequently, as much as streets without camera surveillance have some privacy, safety of human life is enhanced by cameras on this streets tha t act as deterrent to potential criminal acts. Who needs privacy without security anyway? Privacy is very important, but security is more important and as much as the cameras and street lights infringe personal privacy, they enhance personal security, especially in crime zones. The cameras snap breaches of the traffic regulations aiming at vehicle tags and, in some cases, regions drivers. The red light camera does not employ watch cameras to randomly record everything in view on the streets or around the streets. This fact confirms that they at least consider privacy. But does anyone need privacy on the streets? Conversely, availability of traffic lights and cameras helps to control the traffic flow at the intersections. This helps to eliminate conflict flanked by flowing traffic in opposing routes that would instead compel the vehicles to negotiate a protected passage across an intersection, in turn protecting both human lives and any possible destruction of property that could arise from complacence. Considering this importance of the traffic lights, privacy is totally out of place and, therefore, it can never be about it, but rather about road safety. Privacy is not necessary on streets which are public. Traffic lights provide some order, especially in t he big and mostly intersected highways where there is heavy traffic movement, and raises the question of whether we really need traffic lights and cameras in our streets to have human order (Svantesson, 2007). The cameras simply monitor the movements of the vehicles and pedestrians to pinpoint possible collusions and collisions. This acts as a preventive measure to the occurrences of accidents and to improve disaster response rate by the security agencies, to ensure that the victims are saved in case of collisions. Individuals who care about public safety would support the use of traffic lights and cameras to keep vigil of activities in the street. This raises the debate on whether public safety should be protected at the expense of privacy. This is an issue that is yet to receive human consensus with the two groups of pro safety and pro privacy pulling facts on their respective sides. The group supporting public safety consider street lights and cameras to be very essential in driving out the law breakers from the streets and residential places and they accuse those supporting privacy as harboring ill motives. On the other hand, the pro-privacy groups argue that they have a right to their private life free from public scrutiny including government law enforcers. It is, however, acceptable that in addressing the concerns of road users, having traffic lights to assist regulate both the volume and traffic capacity in city roads and major corridors is not only effective but is also necessary. Most governments in the process of providing security to citizens have today deployed lights and cameras in the streets (Mohan, Tiwari Khayesi, 2006). By doing so, citizens are protected from avoidable road accidents and other roadside crimes like hijackings, especially on roads with the highest rate of accidents. By the way equal protection would be provided against other criminal acts like robbery, for potential criminals would not dare commit any unlawful acts under the watchful eyes of the cameras. We have to admit that the rate of crime is high in areas without security cameras and with high levels of privacy. In short, if privacy is prioritized, security is compromised and, if one has to choose a side, security will be chosen. Traffic cameras in most cases help detect individual drivers who are reckless and are likely to cause accidents while at the same time providing useful information to prosecuting authorities in case criminal acts are committed within the view of these cameras. The cameras are set in a way that no photographing takes place without a violation of the street and road laws. They are triggered by rule violations and they do not go off when people need privacy. No one needs privacy in violation of the road laws (John, 2011). The road has sensors embedded and when a driver enters a section against the light, they get photographed as they trigger the cameras. John (2011) writes that in the same way, drivers speeding beyond specified limits trigger the speed cameras to photograph them. In brief, without the cameras and street lights, there would be gross law violation on the roads leading to multiplication of accidents. The concerns of privacy in application of the laws are very minor as pointed out earlier public streets do not need to have privacy, but need to be monitored. This in turn ensures easy prosecution of offenders and getting rid of serial offenders from the society. Informative Section To avoid the use of traffic cameras for the sake of privacy, the society must commit to being better road users. This can only be done by ensuring that individuals who use these roads are fair enough to themselves, especially to their lives, and safety of other citizens. The traffic cameras job of aiding a regulation mechanism for excessive speeds on the part of motorists would then be eliminated and that would be an important first step to getting rid of the gadgets from these streets entirely (Damjanoviski, 2005). Since individuals would not like it when their reckless driving turns into injuries and possible deaths, it is important to make respect of the simple traffic rules a number one prioriy. However, it remains a dream that has for the longest time been a mirage. One of the most camera infested countries in the world is the UK, with almost every street in major towns under surveillance. Several United Kingdom research studies have consistently shown that cameras are very effective in saving lives, rather than having the traffic police officers doing their daily traffic control duties. This is besides the fact that several useful footages are recorded for non traffic related offences (Svantesson, 2007). Consider an example where a citizen is to make an emergency call, and then the security system at the police identifies the callers location followed by instant monitoring of the place on the nearest camera for the recent activities. This allows tracing the crime in the region and possible arrest of the culprits. From one side, this is superb, but from the other, the fact that the system identifies the caller location means that every other time with or without the call the people in the area are photographed and scrutinized (John, 2011). This infringes the privacy and is against the eighth amendment on the bill of rights (Bill of Rights Transcript Text, 1789). It actually seems to be a government tactic to control all the aspects of human life through use of surveillance cameras. Eventualy, the society might end up getting trailed, analyzed, with profiling and flagging their daily lives to unimaginable degree. This fact is a serious concern with the continuous erection of the survei llance cameras on the streets throughout the cities and towns. The cameras are installed on city streets, public ways, alleys, street sidewalks and open park spaces. Consider alleys without the cameras or lights and imagine the kind of crime that would be expected (Mathieu, 2008). As much as we demand privacy, there are areas that need the cameras for security purposes. The security watch-units can explore other options that would satisfy the public concerns of privacy and help to administer security. Considering the fact that the persons watching the cameras and scrutinizing them undergo training, makes the protocol strict focusing only on the necessities which are public safety and traffic (Traffic Management Center: Rhodeways). While some believe that the cameras and traffic lights have considerably reduced crime and traffic rules flaws in areas where they are installed, some people argue that the equipment pushes the crime to other areas. Their arguments simply endorse spreading of the systems to areas where they are not installed. In other words, they are arguing that crime takes place in areas where there are no cameras and there is adequat e privacy. In essence, one can argue along with them that the need for privacy is an endorsement for crime and traffic law breaking. Conclusion There is no possibility of eliminating the street lights and cameras just for the purpose of privacy. Damjanoviski (2005) argues that many countries and societies have gone beyond self-centered privacy outcry to embrace the technology which is fail proof in combating crime and traffic law breaking. In short, the concern that the cameras and street lights are an invasion of privacy comes from people who are either self-centered or have criminal intentions. Despite the fact that most of the roads and highways are equipped with the traffic lights and traffic cameras such as the CCTVs (Catalano, 2011), there is still a need to know how to use these equipments so as to avoid accidents in our roads (Amanzholov, 2008). In case the call for privacy was to be heeding, prior education and public awareness on how to behave on the roads either by drivers or pedestrians is necessary. This can also help in reducing the level of illiteracy of the people who use the public street daily, since they w ill be able to know how to go about traffic lights and how to drive safely. This will also help civilians to avoid crime prone areas. Road accidents could be avoided to a large extend. To enforce this to the drivers, the traffic lights and cameras come in handy. Catalano (2011) writes that crime prone areas in cities are normally in alleys, sideways and park zones. If patrol police were to monitor them, citizens would still complain of the failure because they would not be in position to tell all the crimes that are committed. This is why the cameras and street lights serve important roles in monitoring. It is, however, important to nurture ourselves to proper traffic rules and regulations that would help in reducing crime as well as maintaining high levels of safety in our roads and public places. This would have stopped the necessity of the traffic lights and cameras in the first place. By doing this, it is clear that our streets will be pleasant for us only when safe. Consequently, if various measures are put in place to secure the streets from dangerous criminal activities and accidents, all would be protecting the streets thus making an ample atmosphere for people. Privacy takes the second place in comparison to safety in the community. 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Tuesday, November 5, 2019
How to Write Papers for Graduate School
How to Write Papers for Graduate School Graduate study is all about writing, as the thesis or dissertation is the ticket to graduation. However, lots of writing occurs well before the thesis and dissertation are begun. Most graduate courses require students to write term papers. Many beginning graduate students are accustomed to writing papers and approach them in ways similar to undergraduate papers. As students advance and near the end of their coursework, they often look ahead towards the next task (such as preparing for comprehensive exams) and may begin to resent writing papers, feeling that they have already proven themselves as competent students. Both of these approaches are misguided. Papers are your opportunity to advance your own scholarly work and receive guidance to enhance your competence. Take Advantage of Term Papers How do you take advantage of papers? Be thoughtful. Choose your topic carefully. Each paper you write should do double duty - complete a course requirement and further your own development. Your paper topic should meet the course requirements, but it should also relate to your own scholarly interests. Review an area of literature related to your interests. Or you might examine a topic that you are interested in but unsure whether it is complex enough to study for your dissertation. Writing a term paper about the topic will help you determine if the topic is broad and deep enough to fulfill a large project and will also help you determine if it will sustain your interest. Term papers offer a place for you to test ideas but also to make progress on your current research interests. Double Duty Each assignment you write should do double duty: help you advance your own scholarly agenda and get feedback from a faculty member. Papers are opportunities to get feedback about your ideas and writing style. Faculty can help you improve your writing and help you learn how to think like a scholar. Take advantage of this opportunity and dont simply seek to finish. That said, take care in how you plan and construct your papers. Attend to ethical guidelines of writing. Writing the same paper over and over or submitting the same paper for more than one assignment is unethical and will get you into a great deal of trouble. Instead, the ethical approach is to use each paper as an opportunity to fill in a gap in your knowledge. Consider a student in developmental psychology who is interested in adolescents who engage in risky behaviors such as drinking and drug use. While enrolled in a course in neuroscience, the student might examine how brain development influences risky behavior. In a course on cognitive development, the student might examine the role of cognition in risky behavior. A personality course might push the student to look at personality characteristics that influence risk behavior. In this way, the student advances his or her scholarly knowledge while completing course requirements. The student, therefore, should be examining multiple aspects of his or her general research topic. Will this work for you? At least some of the time. It will be better in some courses than others, but, regardless, it is worth a try.
Sunday, November 3, 2019
College Transfer Academic Personal Statement Example | Topics and Well Written Essays - 500 words
College Transfer Academic - Personal Statement Example arger diversity culture with more ideas and innovative resource inputs; and (3) the prospects of bringing my unique interdisciplinary inspiration to University of California. The genuine interest in the fields of Microbiology developed in childhood while living with my grandmother. In poor health, I remember my old grandma who had to ride her bicycle to take me to see a doctor every day. The persistent routine caught the hypertension syndrome because of the tiredness. This provided the impetus and determination to study medicine and biology. In high school, I became more and more interested in biology and was selected into a Biology Olympiad Team of the school to compete for the National Biology Olympiad as a representative of the school. Despite my inability to gain any national prize due to my naivety and lack of training, I was unnecessarily clumsy at doing experiment. During my freshman year, I became a laboratory researcher for one of the courseââ¬â¢s instructors, Dr. Lee. I assisted in the laboratory doing experiments on microbial ecology to explain the global latitudinal diversity gradient phenomenon. The experiment itself was simple, determining heterozygosity of E. coli in different temperatures. However, the wealth of experience gain and the value of internship were realized in terms of the following: First, the microbiology experiment helped me to improve my laboratory skills initially gained from high school through governance and time management. Since I am in charge of the whole experiment and I am in charge of my schedule, I was able to creatively manage time and control the required variables for the indicated experiment. Thirdly, I realized that I am good at an interdisciplinary approach for the reason that was encouraged to explore diverse possibilities through experimentation in the laboratory and come up with interesting experiments I like, such as creating microbial paintings on culture dishes, among others. The lab experience encourages
Thursday, October 31, 2019
On Television Essay Example | Topics and Well Written Essays - 500 words
On Television - Essay Example He goes on questioning whether the television medium presents the topics accurately or imperatively. The problem of the journalists and the news field is focusing on the truth which has chances to get either approved or disapproved. Like what has been discussed in the argument that ââ¬Å"television presentations almost automatically dumb down due to cultural ââ¬âsocial and technological structures of the fieldâ⬠. But according to Bourdieu the documentary series or program takes a little time to reach the likeness or approval of the audience than the story telling session, or dramas. The reason he has analysed is that news reports will be concentrated towards emphasising the true incident which has brought changes in the television production of the news field in a cultural concept, and the relationship that exist between the intellectuals and the public or the political and the social community. The success of the journalism in television media seems to depend mostly on the responsibility that the intellectual takes to reach the political and the social community. He mainly argues the role and the impact of the journalistic field in a television media with the social and cultural structures. He looks at the solution form the perspective of an individual, and so he says that if an individual takes the role of organising a news documentary for a television presentation so cautiously keeping in mind the social and political expectation rather than obliging what the television industry has to impose on a cultural circle. The television has changed the role of the journalistic field, though it has all forms of technologies to present the information true to life, the journalistic media remains a decline among the public. This he finds due to many reasons one would be that television has all the powerful cultural means to present all the recent political as well as social and cultural issues more effectively than the print media, as a result the television industry and
Tuesday, October 29, 2019
American Government Coursework Example | Topics and Well Written Essays - 250 words
American Government - Coursework Example The problem becomes the Federal Law of racial profiling. It is illegal to racial profile. The illegal immigrants that Arizona are targeting come from south of the border. The illegal immigrants are Hispanic looking. In order for the police to do their jobs they would have to racial profile under the state law, or ignoring the state law. The Federal law should rule on this subject. Since the Civil War Federal law has overrode state law. If we do not have a unified code of law than each state might as well be a country by itself. Secondly, racial profiling is wrong. If Arizona profiles Hispanics, the south would be able to profile blacks. Finally Federal law should prevail because every state, including Arizona, had representation when the Civil Rights Movement and racial profiling laws were passed. Majority rules in the United States. Federal law should rule over state law due to history and representation. Since the Civil War, Federal law has superseded state law. Every state sends representation to Congress, thus laws created are made by all states. In order to have a whole country, states must work together. Federal law should take precedent over state law in this case. If states want to have singular law, succession is another
Sunday, October 27, 2019
Blood Sugar and Lipid Profile: Effects of Garlic and Ginger
Blood Sugar and Lipid Profile: Effects of Garlic and Ginger Comparative Efficacy of Garlic and Ginger on Blood Sugar and Lipid Profile of Alloxan Induced Diabetic Mice Amna Masroor Allium sativum and Zingiber officinale are vegetables used for seasoning, flavoring, culinary and in herbal remedies as they hold insulinotropic properties playing significant role in maintaining ÃŽà ² cells helpful to lower blood glucose level in diabetes. Both are also siginificant in lowering blood lipid levels. The experimental trial of 4 week is planned to investigate the comparative effect of ginger and garlic on blood sugar level and lipid profile in alloxan induced diabetic mice. 25 male mice rats weighing between 40 and 50 g will be used for the study. Diabetes will be induced in fasted mice (12hrs) by a single dose intraperitoneal injection of 40 mg/kg body weight of alloxan. The diabetic state will be assessed by measuring the non-fasting plasma glucose concentration 72hrs after alloxan treatment. The rats with a plasma glucose level above 180mg/dl will be selected for the experiment and considered as diabetics. Mice will be divided into 5 groups having 5 in each as: No rmal Control (group 1), Diabetic control (group 2), Diabetic+ garlic (30g/100g diet group 3), Diabetic + ginger (30mg/kg diet group 4) and Diabetic + ginger and garlic (30g/ 100g group 5). In the end of trial the blood sugar and lipid parameters will be checked and compared. INTRODUCTION: Diabetes mellitus and its allied discrepancies is one of the prominent menaces of developing economics. Pakistan is at 6th position however, at the end of the year 2030; approximately 376 million people will be suffered (Wild et al., 2004). Diabetes is a metabolic syndrome that steadily affects different physiological systems of the human body. It is one of the leading causes of mortality in worldwide and, if uncontrolled, can threat multi-organs system (Zakir et al., 2008). Uncontrolled blood glucose is believed to be the cardinal feature in the onset of diabetic difficulties of both type 1 and type 2 (American Association of Diabetic Educators, 2002). Most common type is Type 2 category, while Type 1 diabetes develops in early childhood. Main reasons include sedentary lifestyles, energy rich diet, lack of physical exercise and obesity (Yajnik, 2001). Diabetes is mainly characterized by relative deficiency in insulin secretion or insulin action associated with hyperglycemia and malfunctioning in the metabolism of carbohydrate, lipid and protein. It may also leads to various other complications like cardiovascular disorders, oxidative stress and immune dysfunction may develop (Nogichi, 2007; Rana et al., 2007).Cardiovascular complications are the major cause of morbidity and mortality all across the globe. Increased cholesterol level and LDL oxidation trigger events that initiate atherosclerosis (Matsuura et al., 2008; Andican et al., 2008; Whale and Heys, 2008). To cope with this situation a number of herbal medicines for diabetes mellitus and its allied diseases have been emerged (Alarcon-Aguilara et al., 1998; Marles and Farnsworth, 1995). Drug treatment is obligatory nevertheless, accompanied by various side effects and their effectiveness decreases with the passage of time (Zakir et al., 2008; Lapshina et al., 2006). Physical exercise and diet selection is one of the significant strategies to manage diabetes and its allied complications including immune dysfunction, degenerative and cardiovascular disorder. Allium sativum, Zingiber officinale and their bioactive constituents hold insulinotropic properties playing significant role in maintaining ÃŽà ² cells helpful to address the menace. Garlic (Allium sativum) is an essential vegetable that has been widely utilized as seasoning, flavoring, culinary and in herbal remedies (Rivlin, 2001). Garlic has been shown to have diverse biological activities including antidiabetic, antithrombotic, anticarcinogenic, antiatherosclerotic, antitumorigenetic and various other biological actions (Augusti, 1996).Scientific investigations have depicted that it contains 65% water, 30% carbohydrates along with 5 % of other bioactive components mainly sulfur containing compounds (Milner, 2001). Its important constituents are classified as; sulfur containing compounds and non sulfur containing compounds. Among these organosulphur compounds particularly cysteine sulfoxides and thiosulfinates have greater importance (Tapiero et al., 2004). Allicin (diallylthiosulfinate) and S-allay cysteine are the main thiosulfinates out of which 60-80% is allicin (Lawson et al., 2001).Garlic and its various preparations have potential to lower total plasma cholesterol, reduction in blood pressure and alleviation of blood glucose level (Sterling and Eagling, 2001). Some studies confirmed anti hyperglycemic effects of garlic (Eidi et al., 2006). Garlic may act on blood glucose through various mechanisms and therefore directly lowers blood glucose level by exciting glycogenisis and preventing glycogenolysis and gluconeogenisis in muscles and hepatic (Ebomoyi et al., 2010). The fiber of garlic may also hamper carbohydrate absorption; thereby affecting blood glucose (Gholamali A Jelodar, 2005). Antioxidant property of garlic is another possible mechanism that makes it a contender as antidiabetic agent (Queiroz et al., 2009; Lee et al., 2009). Antioxidant effect of S-allyl cysteine sulfoxide, isolated product from garlic is considered to have antiglycation properties. Different supplementations of garlic hold remarkable effect on cholesterol level, LDL cholesterol and HDL cholesterol. Consumption of garlic and garlic preparations are very useful in regulating plasma lipid levels (Lau, 2006), plasma anticoagulant activity (Pierre et al., 2005; Lawson et al., 1992) and also contributed toward the prevention of atherosclerosis process (Rehman and Lowe, 2006).Ginger is also very effective for lowering blood sugar, cholesterol and triglyceride levels (Bhandari et al., 1998). Ginger (Zingiber Officinale) commonly called Adrak belongs to family Zingiberaceae (Joshi, 2000). It is used in both ways as food additives (Flavor) or as a medicine and it is useful in preventing or treating a variety of human ailments including migraine headache, elevated cholesterol level, hepatotoxicity, burns, peptic ulcers, nausea, vomiting and motion sickness (Robbers and Tyler, 2002).Chemical constituents of ginger are camphene, cineol, zingiberine, gingerol and ÃŽà ²-ph ellandrene (Shinwari et al., 2006). Ethyl acetate extract of ginger produces significant reduction in glucose concentration and also decreases lipid level (Goyal and Kadnur, 2006). Acute dose of aqueous extracts of Z. Officinale rhizome shows hypoglycaemic activity (Kalejaiye et al., 2002). Ginger promotes glucose clearances in insulin responsive peripheral tissues, which is vital in maintaining blood glucose homeostasis (Li et al., 2012). Ginger treatment considerably reduces the both serum cholesterol and triglycerides (Akhani et al., 2004). The ethanolic extract of ginger also appreciably reduces serum total cholesterol and triglycerides and elevates the HDL-cholesterol levels; also, the extract can protects tissues from lipid peroxidation and shows a significant lipid lowering activity in diabetic rats. Objective: The present study is designed to investigate and explore the hypoglycemic and hypolipidemic perspectives of raw garlic and ginger using alloxan induced biabetic mice modeling. Review of Literature: Ahmed and Sharma, (1997) studied on adult Wister rats were fed diet containing 0.5% ginger (group 3) and combination of ginger and garlic (group 4).Their results showed that the combination of garlic and ginger was much more effective in reducing blood serum cholesterol and blood glucose and in increasing HDL cholesterol. Hence a combination of garlic and ginger is much more effective in reducing blood glucose and serum lipids. Bhandari et al. (1998) studied the effect of ginger on cholesterol fed rabbits, after ten weeks, cholesterol fed rabbits had increased cholesterol, serum triglycerides, serum lipoproteins and phospholipids. When extract of ginger was given the remarkably reduction in the cholesterol, serum triglyceride and serum lipid proteins and phospholipids was observed. Ahmed et al. (2000) examined the dietary effect of ginger on antioxidant dependent system in rats, and his results showed that ginger (Zingiber Officinale; 1% w/w) significantly lowered lipid peroxidation by maintaining the activities of the antioxidant enzymes-superoxide dismutase, catalase and glutathione peroxidase in rats. Ackermann et al. (2001) conducted a study to see the effect of garlic on lipid profile and results indicated that garlic preparations had comparatively lower declines (1.2-17.3 mg/dl and 12.4-25.4 mg/dl) in total cholesterol level as compared to whole garlic after 1 and 3 month correspondingly. Bhandari et al. (2005) discovered that ethanolic extract of ginger significantly reduced serum total cholesterol and triglycerides levels and increased HDL-cholesterol level as compared to diabetic rats, and the extract showed a significant lipid lowering activity and protect the tissues from lipid peroxidation. Goyal and Kadnur, (2006) reported that goldthioglucose cause a significant increase in body weight, glucose insulin level and lipid level in mice and when methanol and ethyl acetate extract of ginger were given to mice for eight weeks that produced significant reduction in glucose concentration and lipid level. Amin et al. (2006) studied the hypoglycemic potential of ginger.The aqueous extract ofraw ginger (500mg/kg) was given to the streptozitocin (STZ) induced diabetic rats for seven weeks. Fasting blood serum was examined and results indicated that the raw ginger was very effective in lowering the serum glucose. Afshari et al. (2007) estimated the effect of ginger powder on nephropathy induced by diabetes, and measured the changes in plasma lipid peroxidation, Wistar rats were treated after the grouping of 3 rats in each. Blood sample was collected from the heart of each rat. The results showed that ginger powder caused decrease in lipid peroxidation. Al-Qattan et al. (2008) reported that in STZ-induced diabetic rats which were injected intraperitoneally with ginger extract for seven weeks, the serum glucose was significantly lowered, and the urine protein reduced to the same level as the normal group. Histological examination clearly depicted that ginger effectively reduced the progression of structural nephropathy in diabetic rats. Islam and Choi, (2008) compared the anti-diabetic effects of dietary ginger and garlic in STZ induced Diabetic rats. In this trial 5-week-old male Sprague-Dawley rats were fed a high-fat (HF) diet (22% fat) for 2 weeks and then randomly divided into six groups of eight animals: Normal Control (NC), Diabetic Control (DBC), Ginger Low (GNL), Ginger High (GNH), Garlic Low (GRL), and Garlic High (GRH) groups. Low and High indicate addition of 0.5% and 2.0% freeze-dried ginger or garlic powder in their respective diets.After 4 weeks data of this study suggested that ginger and garlic are insulinotropic rather than hypoglycemic while overall anti-diabetic effects of ginger are better than those of garlic. Shariatzadeh et al. (2008) exhibited the effect of garlic on lowering blood sugar and preventing and curing nephropathy in STZ induced diabetic rats. 32 male Wister rats were randomly divided into control, control+extract, diabetic and diabetic+extract groups (n=8).Treatment with aqueous-ethanolic extract of garlic (50mg/ kg/day) was followed for 4 weeks. The results revealed that there was significant decrease in blood sugar and increase in weight of kidney and volume of cortex,medulla and kidney. Abd-Elraheem et al. (2009) depicted the effect of ginger extract consumption on levels of blood glucose, lipid profile and kidney functions in alloxan induced-diabetic rats. In this study rats (130-150gm) were divided into 4 groups; normal control rats, diabetic control rats, diabetic rats post-treated with ginger and diabetic rats pretreated with ginger. Ginger extract was administered orally for 6 weeks to post-treated and pre-treated rats, and they were compared with the normal and diabetic groups, respectively. Plasma glucose, plasma lipid,plasma creatinine, urea and uric acid levels were reduced significantly in both post-treated and pretreated groups. Bing et al. (2011) conducted a study to evaluate the hypolipidemic effect of enteric-coated ginger and garlic essence tablet on lipid profile of rats fed high-fat diet and hyperlipidemic subjects. One experimental group having hyperlipidemic rats was assigned to orally expose to three different doses of essence tablet for 30 consecutive days. In addition other experimental group of hyperlipidemic subjects received one piece of ginger and garlic essence tablet twice daily. After 30 days the data of serum lipid profile of both group was obtained which depicted that enteric-coated ginger and garlic tablet remarkably improved blood lipid profile in rats fed high-fat diet and hyperlipidemic subjects. Eyo et al. (2011) revealed the comparative hypoglycemic effect of the hypoglycemic increasing dosages of A. cepa, A. sativum and Z. officinale aqueous extract on alloxan -induced diabetic rats. Increasing dosages (200, 250 and 300mg/kg bw ip) of A. cepa, A. sativum and Z. officinale aqueous extracts were given to the diabetic rats for six weeks and after six weeks blood glucose levels were determined and concluded that A. sativum, A. cepa and Z. officinale significantly decreased blood glucose as 79.7%, 75.4% and 56.7% respectively. Ashour et al. (2011) conducted a study was to investigate the short term effect of garlic oil on the antioxidant status as well as insulin level in streptozotocin (STZ) induced diabetic rats. In diabetic rats (two groups), one treated by garlic oil (200 mg/kg b.wt) and the other group treated by vehicle (corn oil; 2 ml / kg b. wt,) for 8 weeks. Results showed the significant increase in levels of superoxide dismutase (SOD), catalase, GPx, C-peptide and insulin on oral administrations of the garlic oil in the diabetic rats. Prasad et al. (2012) investigated hypolipidimic effects of ginger-juice in rat. Albino rats (n=6-12) were administered G.J at single dose (4ml/rat, p.o) as a chronic treatment over period of 21 days. After the 21 days the lipid profile parameters were checked and which indicated that treatment with ginger-juice in rats significantly reduced the total serum cholesterol level and significantly increased the serum HDL-cholesterol. So it was concluded that ginger juice has hypolipidemic effect. Sanghal et al. (2012) conducted a trial to check the comparative efficacy of ginger and garlic on hypertension and hyperlipidemia in rats. In this study total 18 rats were taken and equally divided into three (control, ginger and garlic) groups by random selection. Ginger and garlic (500 mg/kg orally) were given to two separate groups of rats fed on high fat diet for a period of 7 weeks. Blood pressure and lipid profile were measured on day 0 and after 7 weeks. Comparative results depicted that ginger has better although not significant preventive effect on systolic blood pressure and garlic has better preventive effect on lipid levels. MATERIAL AND METHODS: This experiment will be conducted to investigate the comparative effect of garlic and ginger on blood sugar level and lipid profile of alloxan induced diabetic mice. Plant Material: The A. sativum and Z. officinale used for the experiment will be purchased from the Ayub Agricultural Research Institute, Faisalabad. Animal Model: 25 mice weighing 30-35g will be purchased from National Institute of Health, Islamabad and kept in the animal house of the National Institute of Food Science and Technology (NIFSAT), University of Agriculture Faisalabad. They will be maintained at a temperature of 25 à ± 1à °C and relative humidity of 45 to 55% under 12-h light: 12-h dark cycle. They will be fed with normal diet and water ad libitum. Induction of Diabetes Mellitus: Diabetes will be induced in mice by a single intraperitoneal injection of aqueous alloxan monohydrate (40 mg/kg, i.v.) solution. After 72 hrs animals showing serum glucose level above 180 mg/dl (diabetic) will be chosen for the study. Experimental Protocol: The experimental animals will be divided into 5 groups; each group will contain 5 animals: Control group G1 (normal without treatment), diabetic control group G2 (injected with 40mg/kg b.w. of alloxan), diabetic mice treated with 30g/100g diet of garlic for 4 weeks G3, diabetic mice treated with 30g/100g diet of ginger for 4 weeks G4 and diabetic mice treated with 30g/100g diet containing mixture of garlic and ginger G5. Data Collection: Data will be collected for different parameters for body weight, feed and water intake. Collection of Blood Samples: At the end of 4 weeks blood samples will be collected by sacrificing the animals for determination of blood glucose and lipid profile. Proximate Analysis: The proximate analysis of garlic and ginger for moisture, total ash content, crude protein, fat, crude fiber and nitrogen free extract will be done by using the method given by AOAC (1990). Statistical Analysis: The resulting data will be subjected to some appropriate statistical techniques. Reflection | Physiotherapy Placement Reflection | Physiotherapy Placement The Department of Health (DoH) (2003) highlighted the importance for all professions currently regulated by the Health Professions Council to demonstrate competence through continuing professional development (CPD). CPD is a systematic, ongoing, structured process that encourages the development and maintenance of knowledge, skills and competency that assists us in becoming better practitioners (Chartered Society of Physiotherapy (CSP), 2003). As a result of the Health Act (1999) and for registration with the Health Professions Council (HPC), CPD is a legal requirement (HPC Standards of Proficiency, 2007) that must be completed in accordance with the (HPC) Standards of Continuing Professional Development (HPC, 2006). This essay allows for demonstration of life-long learning using evidence from clinical practice and critical evaluation to contribute to my CPD. Learning outcome 5 will be demonstrated throughout this essay. Throughout this essay the reader is directed to the appendices to support theory with evidence of practice. I considered my motivations for undertaking CPD before writing this essay and reflected upon them again on completion (Appendix 1). Demonstrate professional behaviour with an understanding of the fundamental, legal and ethical boundaries of professional practice Beauchamp and Childress (2001) identify four ethical principles; Autonomy, Beneficence, Non-maleficence and Justice. These ethical principles can be used to morally reason whether an action or decision is right or wrong when used in conjunction with a set of guidelines (Kohlberg et al, 1983). Professional codes of conduct are developed within moral, ethical and legal frameworks to help guide and regulate practice (Hope et al, 2008). Every practitioner has clinical autonomy, therefore they are professionally and legally accountable for their actions. The following will discuss the importance of consent and duty of care for both legal and ethical reasons with regards to case 1 (Appendix 2), encounterd on practice placement 6 (PP6). Rule 9 of the HPC standards of conduct, performance and ethics (2008) states you must gain valid consent from a patient for any treatment you may perform or else you could face trial for assault, battery or negligence under civil or criminal law (Hendrick, 2002). It is a fundamental ethical priniciple that every person has a right to exercise autonomy (Article 9; Human Rights Act, 1998) and is reflected in the Core Standards of Physiotherapy Practice (CSP, 2005). Performing a procedure without gaining consent, undermines the moral priniciple of respect for patientà ¢Ã¢â ¬Ã¢â ¢s autonomy and human dignity (Sim, 1986). However, inability for Patient X to conform to the Mental Capacity Act (2005) meant he was treated in his best intrest in adherance to section 1.5 of this act and Rule 1 of the HPC (2008) standards of conduct, performance and ethics. Assuming the medical management of Patient X, a legal and professional duty of care was established (Rule 6; HPC, 2008). As part of this duty and in accordance with standard 2 of the CSP Core Standards of Physiotherapy, all interventions were explained to patient X despite his inability to consent. Had I not treated Patient X on the basis he had swine flu, this would have been failing to do justice to him, acting outside of the Disability Discrimination Act (2005) which states everyone should have equitable access to and utilisation of services regardless of disability and also Article 14 of the Human Rights Act (1998) in that no one should be discriminated against based on their health status. The Bolam Test (1957, cited in Dimond, 1999) states if duty of care to a client is breached and subsequent harm to the patient occurs, professional standards have not been kept and therefore negligence can be assumed. Although not legally binding, the CSP rules of professional conduct effectiv ely have the same status as law and failure to comply with them means they may not only be used in disciplinary hearings but also in legal proceeding as a civil case under the tort law of negligence (Dimond, 1999; Hendrick, 2002). In summary, a sound understanding of the legal implications surrounding consent and duty of care can help avoid unwanted litigation, however they should not undermine the ethical implications. Appendix 3 demonstrates how I have learnt from this experience. Assess the needs of a range of service users and, with reference to current professional knowledge and relevant research, apply, evaluate and modified physiotherapeutic intervention A service users is anyone who utilises or is affected by a registrants service (HPC, 2008). The complex needs of a service user encompass a range of issues including social, environmental, emotional and health related, the extent of which varies from person to person. For the purpose of this essay, the physiotherapeutic management of two patients treated whilst on PP6 with differing severities of chronic obstructive pulmonary disease (COPD) exacerbations (Appendix 4) will be discussed. The National Institue for Health and Clinical Excellence (NICE) guidelines (NICE, 2004) in conjuntion with the guidelines for physiotherapy in respiratory care (British Thoracic Society (BST), 2008) advocates the use of active cycle of breathing technique (ACBT) with expiratory vibrations on the chest wall for the treatment of COPD to help aid airway clearance. Inability for patient A to comply with ACBT indicated the use of manual hyperinflation (MHI) to passively inflate the lungs and aid mucocillary transport (Ntoumenopoulos, 2005). As identified by Finer et al (1979), atelectasis is a common problem observed in mechanically ventilated patients for which MHI has been found to be beneficial in reducing it in a well controlled clinical trial by Stiller et al (1996), scoring a PEDro rating of 6/10. Absence of a cough reflex in patient A, resulted in sputum retention and the increased risk of infection indicating the use of suctioning (Pryor and Prasad, 2002) by which, copious amounts of viscous secretions were cleared. Shorten et al (1991) supports the use of saline instilation to loosen secretions prior to suctioining however, conflicting arguments by Blackwood (1999) and Kinloch (1999) question its effectiveness. Patient Bà ¢Ã¢â ¬Ã¢â ¢s compliance with ACBT replaced the need for MHI and suctioning. Patient A developed bilateral shoulder subluxations due to his lengthy intubation for which subluxation cuffs were applied, as suggest by Zorowitz et al (1995) with positive effect. Despite this study being on stroke patients, the results can be generalised to other patient groups as proved. The importance of mobilising patients with regards to respiratory function is highlighted by Ciesla (1996), however mobilisation of critically ill patients is restricted as they are often non-ambulatory. A high quality, randomised control trial using fifty-six participants by Mackay et al (2005), identified mobilisation as superior to other respiratory techniques, therefore Patient B was encouraged to sit out and treated using a graduated walking program. In the case of Patient B, mobilisation constitutes any change in position therefore the use of postural drainage positions and positioning into the cardiac chair setting on the bed were used (BTS, 2008). The range of problems service users present with means practitioners need to be adaptable, drawing on current evidence, professional knowledge from different fields of physiotherpy practice and experiences through CPD to deliever indiviualised patient-centred care. Appraise self management of a caseload and modify practice accordingly, demonstarating effective teamwork and communication skills Caseload management typically refers to the number of cases handled in a certain timeframe by an individual for which they have a duty of care towards (Scottish Executive, 2006). It is the management of time effectively through appropriate priority-setting, delegation, and allocation of resources to meet the service demand of its users (Curtis, 2002). Self-management of a caseload and adaptability to changing circumstances is expected of a registrant (HPC, 2008). Well developed time management skills can make a workload more manageable and improve the effectiveness of treatments and quality of time with patients. Prioritising patients to the order in which they will be seen based on their needs is encouraged by SARRAH (2010), however Nord (2002) argues whether it can be justified to prioritise those in most need if their potential benefit may not be as great as those in less need. In my experience prioritisation is dependant on a variety of factors for example, the trust where PP6 was completed, enforced protected meal times which did not run alongside staff meal times. Therefore, to prevent there being a void in the day, patients were still prioritised according to need but considertation had to be given to see patients that would be eating first and treat those that would not be during protected meal times. It is essential to consider that a therapists workload includes not only patient care, but also admistrative and research tasks in which delegation to others can be a valuable stratergy to assist with workload mangement. Curtis, (1999), identifies the need for practioners to show greater awareness of other disciplines competancies so delegation can be more effective. Feedback systems should be enforced to ensure task completion and objectives are being met (Curtis, 2002). Inter-professional collaboration refers to the process by which different disciplines work together to improve healthcare (Zwarenstein et al, 2009). Poor collaboration amongst healthcare professionals contributes to problems in quality of patient care and consequently poorer outcomes (Zwarenstein and Byrant, 1997). Liaison with members of the multi-disciplinary team (MDT) is encouraged by Shortell and Singer (2008) as practitioners are less likely to work off their own autonomy, ensuring patient safety, as demonstrated during handover in (Appendix 5). The learning objectives on PP6 to develop MDT collaboration and caseload management have been achieved as demonstrated in the feedback from my educator (Appendix 6) which identifies that improvement in self confidence will allow further development of the skills discussed. Demonstrate partnership with more junior students and/or appropriate others through the development of mentoring skills Mentoring is a process aimed at transfering knowledge, skills and psycological support from a more experienced person to a less experienced person, where the desired outcome is for both persons to achieve personal and professional growth (Anderson, 1987). An effective mentor facilitates, guides and empowers the mentee in becoming an independent learner (Coles, 1996) in which the relationships developed are based upon mutal respect, trust, confidentiality and shared beliefs and values (Lyons et al, 1990). The CSP (2005) acknowledges the importance of intergrating mentorship into CPD, in which the mentor develops a range of skills transferable to other CPD activities. This section focuses on peer mentoring as a concept, its practice and clinical application on an informal basis. Having identified the characteristics of a mentor (CSP, 2005), a SWOT analysis (Appendix 7) was completed to assist recognition of my personal learning needs. There are four stages to the mentoring life cycle (Appendix 8), in which the mentor needs to adopt and develop new skills to accommodate the mentee and guide them through the process. A qualitative study using a moderate sample size by Chan and Wai-Tong (2000) encourages the use of learning contracts (Appendix 9) to help establish rapports and facilitate autonomous learning which aids progression to stage two of the cycle. This is further supported in a recent review of the literature by Sambunjak et al (2009). Gopee (2008) recognises the importance of analysing the menteeà ¢Ã¢â ¬Ã¢â ¢s needs. Foster-Turner (2006) states that different people approach the learning process in different ways therefore, matching the learning styles of the mentor and mentee will produce a more productive and successful relationship (Mumford, 1995; Hale, 2000). Honey and Mumford (1992) suggested people tend to have a predominant learning style and can be classified as activists, reflectors, theorists or pragmatists (Appendix 10). Boud (1999) identifies raising self-awareness as an essential tool used in lifelong leaning and through analysis of learning styles using Honey and Mumfordà ¢Ã¢â ¬Ã¢â ¢s (1992) questionnaire, this allowed for reflection on the style of learning that would best suit the mentee to help meet their learning needs (Foster-Turner, 2006) (Appendix 11). As identified by the learning style inventory, the mentee and myself were both reflective learners, therefore we arranged sessions where we could dreflect on a clinical experience and discuss how new learning could be applied to future events. A feedback form from the mentee (Appendix 12) an a SWOT analysis (Appendix 13) demonstrates how through increased self-awareness and review of the literature, I have developed a better understanding of the mentoring process, the skills required and its application in into clinical practice. Developing others is central to current and desired practice (DoH, 2000a, 2000b, 2001, 2002) in which mentorship offers all the key attributes to the process. Preparation of an individual for this role, through self assessment, is central to its success, in which the skills developed are lifelong and can enable development into management and leadership roles later on in life. Demonstrate skills of career-long learning Lifelong learning is used synonymously with CPD and is concerned with practitioners critically reviewing their skills and knowledgebase with the ultimate goal of providing a better standard of care to all service users (French and Dowds, 2008). A recent inquest into a practitioner who did not maintain his competencies, demonstrates the possible consequences of poor CPD (Appendix 14). Appendix 15 details a range of formal and informal activities that can be undertaken to contribute towards CPD, evidence of which can be documented in a portfolio. The importance of staff development is recognised by the DoH documents (2000a, 2000b, 2001, 2002) which sets out the Governments vision of an NHS that prepares allied health professionals with the skills to take advantage of wider career opportunities and realise their potential. By using the competency based framework; The NHS Knowledge and Skills Framework (2004), physiotherapists can participate in development reviews which identify development opportunities and contribute to the fulfilment of personal development plans.
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